Born in Taipei, Taiwan, in 2010, Alysa began studying piano at the age of five and started playing harmonica at seven. Since the age of nine, she has focused on the chromatic harmonica under the guidance of Chaoteng Chang. 

In 2023, Alysa won 1st Prize in the Solo Chromatic Open Category at the Taiwan Harmonica Music Festival. In 2025, she was awarded 3rd Prize in Solo Chromatic, Youth Category at the World Harmonica Festival 2025, becoming the first Taiwanese performer to place among the top three in this category. At the same festival, she also achieved remarkable success in the Open Category, winning 1st Prize with 111 Duo and 2nd Prize with 111 Quintet. 

Since co-founding 111 Trio in 2022, Alysa has explored the expressive possibilities of the chromatic harmonica in chamber music and cross-instrument collaboration. In 2025, the ensemble expanded into 111 Quintet for the World Harmonica Festival and later presented Twin Triumph, an award-winning concert in May 2026. In June 2026, Alysa performed with the Mark Wu Tango Quintet in Voices of Reeds • Island Tango at the House of Friendship of the Rotary International Convention in Taipei. 

Alysa currently studies with Chaoteng Chang. She has also received coaching in musical interpretation and stage performance from Korean harmonica virtuoso Jongseong Park (박종성). In the field of tango music, she continues to work with Taiwanese bandoneon master Mark Wu (Wu Yung-lung), broadening both her artistic vision and musical versatility.